Fabrication of astaxanthin emulsion and effect of cellulose derivatives

Introduction: Astaxanthin, a highly active oxidant, possesses potential effect on human health. However, with the oily characteristic, ability to disperse in an aqueous environment has limited its application. Therefore, aim of this study is fabrication stable astaxanthin emulsion water. Methods: In study, was fabricated using polysorbate (tween 60/80) or lecithin. The dispersing methods magnetic stirrer and stator-rotor homogenizer were applied compared. cellulose derivatives (sodium carboxymethyl (CMC), hydroxypropyl (HPC), hydroxyethyl (HEC), methylcellulose (HPMC)) system investigated. samples characterized dynamic light scattering (DLS), Brookfield viscometer Fourier transform infrared (FTIR) spectroscopy. Results: homogenization could provide small Z-average value (~ 500 nm). lecithin maintained red color homogeneity even after 5 months. Tween 80 had worst degradation because presence double bonds surfactant’s molecular structure. addition soluble significantly reduce particle size polydispersity by stirrer. it not ensure protection when phase separation detected many polymers. FTIR spectra viscosity results revealed strong interaction CMC, HEC, HPC, which might be reason for low stability system. HPMC exhibited best capability stabilize preserve emulsion. Without high-energy method, 482 nm (polydispersity index: 0.51) obtained HPMC-lecithin Conclusions: A (up months) successfully. conventional form better single surfactant. assist have DLS stirring method. Lecithin showed performance preservation than Strong interactions HPC detected. lower high stability. open new approach fabricating shear mixing